A decent script that matches your actresses as best as it can and best slider settings you can find (look in this forum; most, if not all, are referenced. If most of your actresses are of a temper in range 1-33 go for an Easy fil, if they are 34-66 go for Moderate, 67+ go for Hard. Make sure you pick best writer for the film type and genre and your level.
Once you have a decent(ish) script asign the actressses that fit the requirements the best and the best directore. Once again, slider settimgs should be available via a search in this forum. Check the highest settings in the three optional extra and off you go ... good luck!
Oh, and higher level actresses will do better, so level them up by getting them to do job.